Publications

Winbo A, Ramanan S, Eugster E, Jovinge S, Skinner JR, Montgomery JM. 2020. Functional coculture of sympathetic neurons and cardiomyocytes derived from human-induced pluripotent stem cells. Am J Physiol Heart Circ Physiol 319(5):H927–H937.

Marshall LL, Killinger BA, Ensink E, Li P, Li KX, Cui W, Lubben N, Weiland M, Wang X, Gordevicius J, Coetzee GA, Ma J, Jovinge S, Labrie V. 2020. Epigenomic analysis of Parkinson’s disease neurons identifies Tet2 loss as neuroprotective. Nat Neuro.

Loyaga-Rendon RY, Fermin D, Jani M, Gonzalez M, Grayburn R, Lee S, Dickinson MG, Manandhar-Shrestha NK, Boeve T, Jovinge S, Leacche M. 2020. Changes in heart transplant waitlist and posttransplant outcomes in patients with restrictive and hypertrophic cardiomyopathy with the new heart transplant allocation system. Am J Transplant. 

Buikema JW, Lee S, Goodyer WR, Maas RG, Chirikian O, Li G, Miao Y, Paige SL, Lee D, Wu H, Paik DT, Rhee S, Tian L, Galdos FX, Puluca N, Beyersdorf B, Hu J, Beck A, Venkamatran S, Swami S, Wijnker P, Schuldt M, Dorsch LM, van Mil A, Red-Horse K, Wu JY, Geisen C, Hesse M, Serpooshan V, Jovinge S, Fleischmann BK, Doevendans PA, van der Velden J, Garcia KC, Wu JC, Sluijter JPG, Wu SM. 2020. Wnt activation and reduced cell-cell contact synergistically induce massive expansion of functional human iPSC-derived cardiomyocytes. Cell Stem Cell 27(1):50–63.e5. 

Li G, Tian L, Goodyer W, Kort EJ, Buikema JW, Xu A, Wu JC, Jovinge S, Wu SM. 2020. Correction: Single cell expression analysis reveals anatomical and cell cycle-dependent transcriptional shifts during heart development. Development 147(7).

Milliron HY, Weiland MJ, Kort EJ, Jovinge S. 2019. Isolation of cardiomyocytes undergoing mitosis with complete cytokinesis. Circ Res 125(12):1070–1086. 

Marinkovic G, Larsen HG, Yndigegn T, Szabo IA, Mares RG, de Camp L, Weiland M, Tomas L, Goncalves I, Nilsson J, Jovinge S, Schiopu A. 2019. Inhibition of pro-inflammatory myeloid cell responses by short-term S100A9 blockade improves cardiac function after myocardial infarction. Eur J Heart 40(32):2713–2723.

Tarnawski L, Eugster E, DeCamp L, Jovinge S. 2019. The efficacy and safety of Sendai viral reprogramming of mouse primary cells using human vectors. Cell Reprogram 21(2):78–88.

Kort EJ, Jovinge S. 2019. Streamlined analysis of LINCS L1000 data with the slinky package for R. Bioninformatics.

Li G, Tian L, Goodyer W, Kort EJ, Buikema JW, Xu A, Wu JC, Jovinge S, Wu SM. 2019. Single cell expression analysis reveals anatomical and cell cycle-dependent transcriptional shifts during heart development. Development 146(12). 

Malinowski M, Jazwiec T, Goehler M, Quay N, Bush J, Jovinge S, Rausch MK, Timek TA. 2019. Sonomicrometry-derived 3-dimensional geometry of the human tricuspid annulus. J Thorac Cardiovasc Surg 157(4):1452–1461.e1.

Bergström U, Jovinge S, Persson J, Jacobsson LTH, Turesson C. 2018. Effects of treatment with Adalimumab on blood lipid levels and atherosclerosis in patients with rheumatoid arthritis. Curr Ther Res Clin Exp 89:1-6. 

Ederoth P, Dardashti A, Grins E, Brondén B, Metzsch C, Erdling A, Nozohoor S, Mokhtari A, Hansson MJ, Elmér E, Algotsson L, Jovinge S, Bjursten H. 2018. Cyclosporine before coronary artery bypass grafting does not prevent postoperative decreases in renal function: A randomized clinical trial. Anesthesiology 128(4):710–717.

Schüssler-Lenz M, Beuneu C, Menezes-Ferreira M, Jekerle V, Bartunek J, Chamuleau S, Celis P, Doevendans P, O’Donovan M, Hill J, Hystad M, Jovinge S, Kyselovič J, Lipnik-Stangelj M, Maciulaitis R, Prasad K, Samuel A, Tenhunen O, Tonn T, Rosano G, Zeiher A, Salmikangas P. 2016. Cell-based therapies for cardiac repair: a meeting report on scientific observations and European regulatory viewpoints. Eur J Heart Fail 18(2):133–141.

Li W, Sultana N, Siraj N, Ward LJ, Pawlik M, Levy E, Jovinge S, Bengtsson E, Yuan XM. 2016. Autophagy dysfunction and regulatory cystatin C in macrophage death in atherosclerosis. J Cell Mol Biol 20(9):1664–1672.

Olsson P, Theander E, Bergström U, Jovinge S, Jacobsson L, Turesson C. 2016. Multiplex cytokine analysis in patients with rheumatoid arthritis require use of agents blocking heterophilic antibody activity. Scand J Rheumatol 46(1):1–10.

Ederoth P, Grins E, Dardashti A, Brondén B, Metzsch C, Erdling A, Nozohoor S, Mokhtari A, Hansson MJ, Elmér E, Algotsson L, Jovinge S, Bjursten H. 2016. Ciclosporin to protect renal function in cardiac surgery (CiPRICS): a study protocol for a double-blind, randomized, placebo-controlled, proof-of concept study. BMJ Open 6(12):e012299.

Kort EJ, Croskey L, Scibienski T, Rajasekaran S, Jovinge S. 2015. Circulating progenitor cells and childhood cardiovascular disease. Pediatr Cardiol 37(1):1–7.

Bergmann O, Zdunek S, Felker A, Salehpour M, Alkass K, Bernard S, Sjostrom SL, Szewczykowska M, Jackowska T, dos Remedios C, Malm T, Andrä M, Jashari R, Nyengaard JR, Possnert G, Jovinge S, Druid H, Frisén J. 2015. Dynamics of cell generation and turnover in the human heart. Cell 161(7):1566–1575

Raulf A, Horder H, Tarnawski L, Geisen C, Ottersbach A, Röll W, Jovinge S, Fleischmann BK, Hesse M. 2015. Transgenic systems for unequivocal identification of cardiac myocyte nuclei and analysis of cardiomyocyte cell cycle status. Basic Res Cardiol 110(3):33 

Braun OÖ, Bico B, Chaudry U, Wagner H, Koul S, Tydén P, Scherstén F, b, Svensson PJ, Gustav Smith J, van der Pals J. 2015. Concomitant use of warfarin and ticagrelor as an alternative to triple antithrombotic therapy after an acute coronary syndrome. Thromb Res 135(1):26–30

Tarnawski L, Xian X, Monnerat G, Macauley IC, Malan D, Borgman A, Wu SM, Fleischmann BK, Jovinge S.  2015.  Integrin based isolation enables purification of murine lineage committed cardiomyocytes.  PLoS One 10(8):e0135880.

Bergmann O, Jovinge S. 2014. Cardiac regeneration in vivo: Mending the heart from within? Stem Cell Res 13(3 Pt B):523–531

Pontén A, Walsh S, Malan D, Xian X, Schéele S, Tarnwaski L, Fleischmann BK, Jovinge S. 2013. FACS-based isolation, propagation and characterization of mouse embryonic cardiomyocytes based on VCAM-1 surface marker expression. PLoS One 8(12):e82402

Ubachs FJ, Sörensson P, Engblom H, Carlsson M, Jovinge S, Pernow J, Arheden H. 2012. Myocardium at risk by magnetic resonance imaging: Head-to-head comparison of T2-weighted imaging and contrast enhanced steady-state free precession. Eur Heart J Cardiovasc Imaging 13(12):1008–1015

ORIGIN Trial Investigators, Bosch J, Gerstein HC, Dagenais GR, Diaz R, Dyal L, Jung H, Maggiono AP, Probstfield J, Ramachandran A, Riddle MC, Rydén LE, Yusuf S*. 2012. n-3 fatty acids and cardiovascular outcomes in patients with dysglycemia. N Engl J Med 367(4):309–318
*Jovinge S is one of 2737 collaborators

ORIGIN Trial Investigators, Gerstein HC, Bosch J, Dagenais GR, Diaz R, Jung H, Maggioni AP, Pogue J, Probstfield J, Ramachandran A, Riddle MC, Rydén LE, Yusuf S*. 2012. Basal insulin and cardiovascular and other outcomes in dysglycemia. N Engl J Med 367(4):319–328
*Jovinge S is one of 2737 collaborators

Bergmann O, Jovinge S. 2012. Isolation of cardiomyocyte nuclei from post-mortem tissue. J Vis Exp (65). doi:10.3791/4205

Forberg JL, Khoshnood A, Green M, Ohlsson M, Björk J, Jovinge S, Edenbrandt L, Ekelund U. 2012. An artificial neural network to safely reduce the number of ambulance ECGs transmitted for physician assessment in a system with prehospital detection of ST elevation myocardial infarction. Scand J Trauma Resusc Emerg Med 20:8

Bergmann O, Zdunek S, Frisén J, Bernard S, Druid H, Jovinge S. 2012. Cardiomyocyte renewal in humans. Circ Res 110(1):e17–18 

Mega JL, Braunwald E, Wiviott SD, Bassand JP, Bhatt DL, Bode C, Burton P, Cohen M, Cook-Burns N, Fox KA, Goto S, Murphy SA, Plotnikov AN, Schneider D, Sun X, Vergeugt FW, Gibson CM, ATLAS ACS2-TIMI 51 Investigators*. 2012. Rivaroxaban in patients with a recent acute coronary syndrome. N Engl J Med 366(1):9–19
*Jovinge S is one of 860 collaborators

Engblom H, Strauss DG, Heden B, Hedström E, Jovinge S, Götberg M, Erlinge D, Wagner GS, Arheden H. 2011. The evaluation of an electrocardiographic myocardial ischemia acuteness score to predict the amount of myocardial salvage achieved by early percutaneous coronary intervention: Clinical validation with myocardial perfusion single photo emission computed tomography and cardiac magnetic resonance. J Electrocardiol 44(5):525–532

Walsh S, Nygren J, Pontén A, Jovinge S. 2011. Myogenic reprogramming of bone marrow derived cells in a W41Dmd(mdx) deficient mouse model. PLoS One 6(11):e27500

Fuegemann CJ, Samraj AK, Walsh S, Fleischmann BK, Jovinge S, Breitbach M. 2010. Differentiation of mouse embryonic stem cells into cardiomyocytes via the hanging-drop and mass culture methods. Curr Protoc Stem Cell Biol 1(1F.11)

Walsh S, Pontén A, Fleischmann BK, Jovinge S. 2010. Cardiomyocyte cell cycle control and growth estimation in vivo: An analysis based on cardiomyocyte nuclei. Cardiovasc Res 86(3):365–373

Ubachs JF, Engblom H, Erlinge D, Jovinge S, Hedström E, Carlsson M, Arheden H. 2010. Cardiovascular magnetic resonance of the myocardium at risk in acute reperfused myocardial infarction: Comparison of T2-weighted imaging versus the circumferential endocardial extene of the late gadolinium enhancement with transmural projection. J Cardiovasc Magn Reson 12:18

Magnusson M, Jovinge S, Shahgaldi K, Israelsson B, Groop L, Melander O. 2010. Brain natriuretic peptide is related to diastolic dysfunction whereas urinary albumin excretion rate is related to left ventricular mass in asymptomatic type 2 diabetes patients. Cardiovasc Diabetol 9:2

Nilsson-Ohman J, Frederickson GN, Nilsson-Berglund LM, Gustavsson C, Bengtsson E, Smith ML, Agardh CD, Agardh E, Jovinge S, Gomez MF, Nilsson J. Tumor necrosis factor-alpha does not mediate diabetes-induced vascular inflammation in mice. Arterioscler Thromb Vasc Biol 29(10):1465–1470

Hedström E, Engblom H, Frogner F, Aström-Olsson K, Ohlin H, Jovinge S, Arheden H. 2009. Infarct evolution in man studied in patients with first-time coronary occlusion in comparison to different species: Implications for assessment of myocardial salvage. J Cardiovasc Magn Reson 11:38

Wallentin L, Becker RC, Budaj A, Cannon CP…PLATO Investigators, Freij A, Thorsén M*. 2009. Ticagrelor versus clopidorel in patients with acute coronary syndromes. N Engl J Med 361(11):1045–1057
*Jovinge S is one of 1118 collaborators

Carlsson M, Ubachs JF, Hedström E, Heiberg E, Jovinge S, Arheden H. 2009. Myocardium at risk after acute infarction in humans on cardiac magnetic resonance: Quantitative assessment during follow-up and validation with single-photon emission computed tomography. JACC Cardiovac Imaging 2(5):569–576

Magnusson M, Jovinge S, Rydberg E, Dahlöf B, Hall C, Nielsen OW, Grubb A, Willenheimer R. 2009. Natriuretic peptides as indicators of cardiac remodeling in hypertensive patients. Blood Press 18(4):196–203